This study demonstrates that low-intensity infrasound (4-20 Hz, 79-86 dB) applied for 60 minutes significantly enhances the proliferation and inhibits apoptosis of bone marrow mesenchymal stem cells (BMSCs) in vitro, likely through increased expression of survivin, a protein that promotes cell survival and division. These findings suggest that infrasound could improve the viability of BMSCs, addressing a critical limitation in their therapeutic use for tissue repair in conditions like cerebral ischemia, stroke, or traumatic brain injury. For medical professionals, this highlights the potential of low-intensity infrasound as a non-invasive, supplementary method to enhance BMSC survival during transplantation, potentially improving outcomes in regenerative therapies, though further research is needed to validate its clinical efficacy and optimal application protocols.
Owners of the Infrasound 8 and CHI Palm might use them to help improve the health and growth of special cells used in treatments for conditions like stroke, brain injuries, fracture repair, or other situations where damaged tissue needs repair. The study suggests that applying the device at low settings (Acute setting for the CHI Palm) for 60 minutes can encourage these cells to grow better and survive longer. This could make the cells more effective when used to help fix damaged areas in the body, potentially leading to better recovery outcomes. This is a preliminary study.