The Science of Infrasound - CHI Institute

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Clinical Studiers, International Research, and the Future of Infratonic Healing

For over three decades, the CHI Institute has supported scientific exploration into the therapeutic effects of Infratonic technology. This curated library of peer-reviewed studies and experimental research demonstrates how infrasound and stochastic resonance are reshaping healing—from cellular regeneration to emotional regulation and equine recovery. Below, you’ll find a collection of clinical findings that validate and expand the understanding of vibrational therapy and its profound impact on the human and animal body.

From Innovation to Validation

The 40-Year Journey of CHI Infrasound Therapy

In the blog post below, The Science of Healing: Therapeutic Infrasound is Evidence-Based, is a summary outline that consolidates the individual studies listed beneath it. It presents the chronology and history of CHI Institute’s technologies as a cohesive narrative, tracing the evolution of CHI-developed infrasound from its inception in 1985 to its recognition in peer-reviewed medical literature.

This article highlights key milestones, clinical outcomes, and biochemical mechanisms that demonstrate the safety and effectiveness of therapeutic infrasound. Whether you’re looking for a concise overview or an entry point into deeper scientific research, this post offers a clear foundation for understanding the evidence behind CHI Infrasound therapy.

Explore the Evidence. Experience the Difference.

Therapeutic Infrasound is Evidence-Based

CHI Palm Infrasound Infratonic

The Science of Healing: Therapeutic Infrasound is Evidence-Based

This blog post traces the history of CHI Institute’s therapeutic infrasound technology, from its creation in 1985 to its recognition in mainstream medical literature. A great starting point for anyone interested in the science behind CHI Infrasound.

June 10, 2025

Scientific Studies Behind the CHI Infrasound Journey

Dive Deeper: The Research That Validates CHI Technology

1 Infrasound and Audible Sound in Modulating Wound Healing

This research survey examines existing research on infrasound and low frequency sound on wound healing. The studies by Long et…

January 21, 2025

2 Mechanotransduction in skin wound healing and scar formation

The study, "Mechanotransduction in skin wound healing and scar formation: Potential therapeutic targets for controlling hypertrophic scarring," published in Frontiers…

October 17, 2022

3 Mechanotransduction in Osteogenesis

This study provides a comprehensive review of the fundamental concepts of mechanotransduction, the process by which mechanical (and infrasonic) stimuli…

January 1, 2020

4 Infrasound reduces the cardiac fibroblasts: a mechanism

This study demonstrates that low decibel infrasound (4-20 Hz, 79.75-86.11 dB) significantly inhibits angiotensin II (Ang II)-induced proliferation and collagen…

5 Notch Signaling Supports Proliferation of Bone Marrow Stem Cells 2017

This study demonstrates that low-intensity infrasound (4-20 Hz, 79-86 dB) applied for 60 minutes enhances the proliferation of bone marrow…

6 The effect of low-sound pressure infrasound on cerebral ischemia and recharged with rat syntaxes and microtube-related proteins.

Summary Purpose: To explore the impact of low-sound pressure infrasound on the synaptic elements (SYN) and micro-tube-related protein(MAP-2) expressed by the…

January 5, 2015

7 Effects of Infrasound on the Growth of Bone Marrow Mesenchymal Cells

August 21, 2014

8 Osteogenesis promoted by infrasound in vivo and some underlying mechanisms

This study demonstrates that low sound pressure level (LSPL) infrasound (12-20 Hz, <90 dB) applied for 30 minutes twice daily…

September 20, 2013

9 Infrasound increases IGF-1 in focal cerebral Ischemia-Refusion Injury 2008

This study, published in the Chinese Journal of Physical Medicine and Rehabilitation (2008), explores the effects of low-intensity infrasound (Infrasound…

February 7, 2013

10 Infrasound Enhances GFAP Expression Following Cerebral Ischemia-Reperfusion Injury 2013

This study, published in the Chinese Journal of Rehabilitation Theory and Practice (Feb. 2013), investigates the effects of low-intensity infrasound…

February 7, 2013

11 Effects of Infrasound in vitro on Glioma Cells

Garret Yount and colleagues at the California Pacific Medical Center Research Institute in San Francisco evaluated the potential effects of…

12 Infrasound Relieves Symptoms of Diabetic Peripheral Neuropathy

This study on the effect of mechanical stochastic noise (unpredictable infrasound provided by the Infratonic device with 8-13Hz frequency applied…

August 20, 2005

13 Infrasound Restores Joins and Muscle Injuries in Standard-bred Races Horses Part 2

Equine 2 study April 7 2014 This is a continuation of the equine study series. While study 3, the first…

14 Alpha Induces Cooperative Behavior in Nurses

The study from CHI Institute shows that Infratonic therapy, which uses low-frequency sound in the alpha range (8-13 Hz), can…

15 Infrasound reduces Inflammation in the Hocks and Muscles of Horses

This study presents the first two of four equine studies conducted by Ronald Riegel DVM for CHI Institute. The first…

16 Chaos, Infrasound, and the College Entrance Exam

The study investigates the application of Chaos theory to influence the unpredictable dynamics of college entrance exam performance, with the…

17 Vibrational Trembling, Chaos, and EEG

The study "Vibrational Trembling Chaos EEG" shows infrasound from devices like the CHI Palm alters brain activity, impacting neural oscillations…

18 Infrasonic Treatment of Asthma

The study on Infrasound treatment for asthma, utilizing the Infratonic 8000 device, demonstrates significant reductions in asthma symptoms and medication…

February 18, 1987

19 Infrasound synchronizes EEG alpha rhythms

This blinded, placebo controlled neuroscience study by Liu Guo-long MD PhD provides the first electroencephalograph (EEG)-based evidence that infrasonic waves,…

September 20, 1985

20 Infrasound and Digestive Deficiency in Children

This hospital study explores the value of hospitalized children with chronic digestive problems. It selects test subjects based on the…

21 Accelerated Immune Response in Rabbits with Infrasound

The study "Accelerated Immune Response: The Effect of Simulated Emitted Qi on Blood Serum Antibody Level" is significant to the…

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